Keywords
elastic modulus
nanoindentation
proposed workflow
How to Cite
Abstract
Nanoindentation is a method for mapping the mechanical properties of heterogeneous materials. This paper aims to provide a review of this method, the challenges that still remain in spite of recent innovations and future recommendations. Various types of indenters and sample preparation methods, together with displacement-load curves ensure the correctness of operation process and correct manipulation of nanoindentation device. The novelty of this work lies in the proposed workflow in schematic way, that integrates Atomic Force Microscopy (AFM), Density Functional Theory (DFT) and Finite Element Method (FEM) into a single sequence. This approach enables the cross-validation between computational, experimental and quantum mechanical methods, providing a comprehensive characterization of material from macroscale to nanoscale. This workflow serves also as a standardized guideline, that may help to enhance reproducibility and interpretability for bone mechanical properties, thus it can be used for interdisciplinary projects and become a routine tool in material science and biomedical applications.
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