LASER GENERATED GOLD NANOPARTICLES FOR MASS SPECTROMETRY OF LOW MOLECULAR WEIGHT COMPOUNDS
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Keywords

gold nanoparticles; laser generated nanomaterial; low molecular weight compounds; mass spec-trometry; matrix-free laser desorption/ionization; surface‐assisted desorption/ionization

Abstract

Preparation of gold nanoparticles (AuNPs) by pulsed fiber laser (PFL) laser generated nanomaterial (LGN) with the use of 2D galvo-scanner (2D GS) is described. The procedure of covering of custom-made stainless steel MALDI targets containing studied objects via nebulization is also presented. Examples of application of new method (PFL-2D GS LGN and nebulization) in laser desorption/ionization mass spectrometry (LDI MS) analyses are shown. These include tests with amino acids and also low molecular weight polymer. 

https://doi.org/10.7862/rc.2022.1
pdf (english)